PhD Chemical Engineering · BSc Biological Engineering
Arda
Akyel
Bridging pharmaceutical validation, bioprocess engineering, and research — from bench-scale discovery to GMP manufacturing environments.
About
I'm a chemical engineer with a PhD from Montana State University and a career at the intersection of pharmaceutical validation, bioprocess engineering, and applied research. Currently at Arcadis, I lead commissioning, qualification, and validation efforts across greenfield biomanufacturing sites — qualifying complex process equipment from fill-finish to oligonucleotide synthesis.
Before industry, I spent seven years at the Center for Biofilm Engineering researching bacterial enzymatic biomineralization — using microorganisms to seal CO₂ leakage pathways in subsurface environments. That work resulted in five publications, a U.S. patent, and a large-scale field demonstration at a coal-fired power plant in Gorgas, Alabama.
My strongest asset is the ability to move fluidly between rigorous scientific thinking and real-world manufacturing constraints — whether drafting ASTM E2500 risk-based qualification strategies or optimizing enzyme kinetics under harsh pH and temperature conditions.
Experience
Publications & Patent
U.S. Patent — Ureolysis-Induced Calcium Carbonate Precipitation for Sealing Channels and Other Uses
Novel biocementation technology for subsurface sealing applications. Developed from seven years of bench, pilot, and field-scale research.
Education & Certifications
Certifications & Training
- Lean Six Sigma White BeltAveta Business Institute
- Managing Process Safety HazardsAIChE
- Introduction to Process SafetyAIChE
- Introduction to Managing Process Safety HazardsAIChE
- Biosafety for BSL1 & BSL2 Lab WorkersCITI Program / BRANY
- Hazard Communication — GHSOSHA
Skills & Expertise
Validation & Quality
- IQ / OQ / PQ Authorship & Execution
- URS / FRS Documentation
- ASTM E2500 Risk-Based Validation
- 21 CFR Part 11 Compliance
- EU Annex 11 / Annex 15
- GAMP 5
- GDP / GMP
- Deviation & Change Control
- Veeva, SmartSolve, Kneat
Bioprocess & Engineering
- Bioreactors & Reactor Design
- Chromatography (Cytiva, Sartorius)
- Ultrafiltration Skids (Pall)
- CIP / SIP Systems
- Sterile & Aseptic Technique
- Lyophilization
- Fill-Finish Processes
- Upstream / Downstream Processing
- Enzyme Kinetics
Research & Technical
- Experimental Design
- Microbiology & Cell Culture
- Protein Purification
- HPLC & Analytical Methods
- Python & MATLAB
- Scientific Writing
- Technology Transfer
- Team Leadership (up to 10)
- Cross-functional Collaboration
Contact
Get in
touch.
For collaborations, inquiries, or to discuss validation, bioprocess, and research.